Research on the Anatomy of the Dorsal Root Ganglion and its Involvement in the Mechanism of Neuropathic Pain

  • Hongzhou He
  • Haifa Qiao Shaanxi Key Laboratory of Acupuncture and Medicine, China
Keywords: Dorsal Root Ganglion, neuropathic pain, pain mechanism, Neuronal Electrophysiology, chronic pain

Abstract

The dorsal root ganglion (DRG), as one of the key structures in the sensory nervous system, plays a crucial role in the onset and development of neuropathic pain. This paper explores the involvement of the DRG in the mechanism of neuropathic pain, starting with its anatomical structure. First, the basic anatomical characteristics of the DRG and its function in sensory signal transmission are analyzed. Then, the role of the DRG in neuropathic pain is discussed, particularly focusing on the abnormal neuronal activity and molecular mechanisms in chronic pain and hyperalgesia. Finally, the potential of the DRG as a therapeutic target for neuropathic pain is explored, including current treatment methods and future research directions. Through a detailed analysis of the DRG, this study provides new insights into understanding the mechanism of neuropathic pain and its clinical treatment.

Author Biography

Hongzhou He

The dorsal root ganglion (DRG), as one of the key structures in the sensory nervous system, plays a crucial role in the onset and development of neuropathic pain. This paper explores the involvement of the DRG in the mechanism of neuropathic pain, starting with its anatomical structure. First, the basic anatomical characteristics of the DRG and its function in sensory signal transmission are analyzed. Then, the role of the DRG in neuropathic pain is discussed, particularly focusing on the abnormal neuronal activity and molecular mechanisms in chronic pain and hyperalgesia. Finally, the potential of the DRG as a therapeutic target for neuropathic pain is explored, including current treatment methods and future research directions. Through a detailed analysis of the DRG, this study provides new insights into understanding the mechanism of neuropathic pain and its clinical treatment.

References

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Published
2025-02-24
Section
Articles