Nanone interactions in antibody of living systems

Rajasekaran Ekambaram — 2021-12-16

One of the facts about how nanoparticle assemble and act is revealed using carbon value in biomolecule of living system here. This is how the biomolecules interact to bring about a micro or even macro level interaction in system of interest. This study shows micro level understanding can be better utilized from carbon analysis at nano level. I plan to extend this phenomena of change from nano to micro for building large scale applications in human nature. Applications include corrections in both at sequence and structure level for permanent recovery of defective one, adding flavor to the existing biomolecule for faster delivery or recovery etc. I have demonstrated here the active role played by carbon and all. This might be extended to another system of setup where new applications yet to be created. One can extend this phenomena of change from nano to large scale one.

Detection of Mycobacterium Tuberculosis IgM and IgG Antibodies and Associated Risk Factors Among Apparently Healthy Undergraduate Students of a Private University in South-West Nigeria

Seyi Samson Enitan — 2022-02-12

Background: Infection with Mycobacterium tuberculosis (TB) is frequent among Nigerians. Many people are infected without realizing it (asymptomatic) and thus provide a risk of transmission to others. Not only will early treatment prevent TB complications, but it will also help to break the infection cycle in a community.

Objective: The study was conducted to determine the prevalence of Mycobacterium tuberculosis IgM and IgG antibodies and associated risk factors among apparently healthy undergraduate Students of Babcock University, Ilishan-Remo, Ogun State.

Methodology: The serum samples of 100 consenting participants were collected randomly and screened for TB antibodies using Aria TB IgG/IgM Combo Rapid Antibody Test Cassette (CTK Biotech Inc. Poway, CA 92064, USA). A structured questionnaire was administered to consenting students to obtain information on their bio-data (e.g, the age, sex, study level etc.), as well as clinical information regarding their health (History of TB, history of BCG vaccination, use of anti-TB medications, alcohol consumption, smoking habits etc.).

Results: The outcome of this study shows that 15 (15%) out of the 100 participants screened, were positive for TB IgG antibody, while, only 1 (1%) person was positive for TB IgM antibody. There was no significant association (P>0.05) between percentage TB IgG positivity and the socio-demographic characteristics of the study participants (gender, age, study level and tribe), except for religion. The percentage of TB IgG positivity among the study participants was found to be significantly higher than of TB IgM positivity (P<0.05). None of the 15 participants who tested positive to TB IgG indicated any of the signs and symptoms (persistent cough, chest pain, nausea, fever, chills, loss of appetite, fatigue and night sweat) associated with TB), however the only person who tested positive for TB IgM indicated all, except night sweat. Identified risk factors associated with the occurrence of TB IgM include history of TB, lack of BCG vaccination, history of diabetes and physical unfitness.

Conclusion: The findings of this study show that asymptomatic and latent tuberculosis infection exists among the study participants, and that if left untreated, it will progress to active tuberculosis with all of its associated complications, including death. This emphasizes the importance of ongoing public health education, BCG vaccination, and periodic screening to detect asymptomatic cases in the study population in order to break the infection cycle.

Modern Health Science

Nanone interactions in antibody of living systems

Detection of Mycobacterium Tuberculosis IgM and IgG Antibodies and Associated Risk Factors Among Apparently Healthy Undergraduate Students of a Private University in South-West Nigeria