Research on Ion Channels in Dorsal Root Ganglion Neurons
Abstract
Dorsal Root Ganglion (DRG) neurons serve as crucial nodes for pain signal transmission, and their excitability regulation plays a key role in various physiological and pathological processes. Ion channels, as central components in modulating DRG neuron function, are involved in biological processes such as pain conduction, neural signal integration, and plasticity. This paper systematically analyzes the structural characteristics, functional mechanisms, and roles of different types of ion channels in DRG neurons, including sodium channels, potassium channels, calcium channels, and other related channels, particularly in pathological conditions. In light of current research trends, the paper also explores the potential of ion channels as drug targets and in technological applications, while suggesting future research directions. The aim is to provide theoretical support for the diagnosis and treatment of diseases related to DRG neurons.
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