Research Status of Traditional Chinese Medicine in the Treatment of Gastric Precancerous Lesions
Keywords:
gastric precancerous lesions, traditional chinese medicine treatment, current status of research
Abstract
Gastric cancer is an extremely common malignant tumour in China, with high morbidity and mortality rates, posing a serious threat to the life and health of the people. Pre-cancerous gastric lesions are considered to be an important stage in the development of gastric cancer, so timely monitoring of pre-cancerous gastric lesions and effective treatment are the key links in the prevention and control of gastric cancer. Traditional Chinese medicine has been widely used in the treatment of gastric precancerous lesions and has shown its unique advantages. This article systematically describes the etiology and mechanism of this disease and the current status of clinical treatment research, with the aim of providing valuable references for the formulation of clinical treatment plans and the development of related medicines.
References
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[12] Zheng, B. (2024). Clinical efficacy and mechanism of action of Sancao Tiaowei Decoction in the treatment of precancerous lesions of gastric cancer with spleen deficiency and stasis of phlegm and blood syndrome based on network pharmacology study. [Doctoral dissertation, Zhejiang University of Chinese Medicine].
[13] Dai, M., & Zhang, S. (2023). Therapeutic effect of using Huayu Jiedu Tongluo Recipe in the treatment of stomach-collateral stasis-toxin type gastric precancerous lesion and its influence on the expression of inflammatory factors, COX-2, PG I and G-17. Journal of Sichuan of Traditional Chinese Medicine, 41(1), 118-122.
[14] Li, J., Liu, X., & Meng, C. (2024). Exploring the efficacy of Strengthening the Spleen and Resolving Blood Stasis Formula in the treatment of gastric precancerous lesions based on the Correa cascade and its effect on the expression of inflammatory factors in patients. Modern Interventional Diagnosis and Treatment in Gastroenterology, 29(1), 68-73.
[15] Ye, G., Li, K., Jiang, W., et al. (2023). Clinical observation on the effects of Weiqi Decoction in the treatment of chronic atrophic gastritis with spleen and stomach deficiency. Chinese Journal of Integrated Traditional and Western Medicine on Digestion, 31(8), 595-599.
[16] Zhang, H., Zhou, X., & Cao, G., et al. (2024). Intervention effect of Weifuchun on precancerous lesions of gastric cancer rats based on PI3K/Akt signaling pathway. World Journal of Integrated Traditional and Western Medicine, 19(4), 689-693.
[17] Zhu, X., Li, S., Liu, J., et al. (2022). Efficacy of Moluodan in patients with gastric intestinal metaplasia: Analysis of 104 cases. Chinese Journal of Gastroenterology, 27(12), 717-722.
[18] Dai, J., Jin, H., & Meng, L., et al. (2017). Multi-center randomized clinical study of the effect of Curcuma and Pseudo-ginseng on chronic atrophic gastritis. Modern Chinese Clinical Medicine, 24(6), 15-19.
[19] Ye, C., He, Y., & Tang, S., et al. (2024). Clinical study on the effects of Yiweining Capsules combined with Rebamipide Tablet in treating chronic atrophic gastritis with spleen-stomach Qi deficiency syndrome. Chinese Journal of Information on Traditional Chinese Medicine, 31(1), 142-146.
[20] Jin, J., Zhong, H., & Liu, Q., et al. (2022). Comparison of stimulation-induced local changes of expression of local Meckel cell-related proteins and neuropeptides and number of mast cells among acupuncture and moxibustion alone or in combination in chronic atrophic gastritis rats. Acupuncture Research, 47(3), 203-208.
[21] Wang, F., Ye, H., & Chen, X., et al. (2021). Therapeutic efficacy and effect on serum MTL, SS, and GAS levels of chronic atrophic gastritis of spleen and stomach deficiency and cold type by combining Yuanluo Tongjing Acupuncture with Hao Huo Pins. Journal of Sichuan of Traditional Chinese Medicine, 39(8), 195-198.
[22] Guo, Y., & Zhou, F. (2018). Therapeutic efficacy of self-proposed stomach nourishing soup combined with acupoint burrowing in the treatment of chronic atrophic gastritis. Modern Journal of Integrated Traditional Chinese and Western Medicine, 27(26), 2893-2896.
[23] Sun, X., Lv, G., & Jia, J., et al. (2020). Clinical observation on Hewei Zhitong granule combined with auricular acupoint pressing bean in treating Hp positive chronic atrophic gastritis. Chinese Journal of Integrated Traditional and Western Medicine on Digestion, 28(7), 494-498.
[24] Ma, G., Li, L., & Song, Y., et al. (2024). Clinical study on Huangqi Jianzhong Decoction combined with acupoint application in the treatment of atrophic gastritis of spleen and stomach deficiency cold type. Chinese Health Care, 42(22), 18-21.
[2] Wei, Y., Su, T., Ma, Y., et al. (2023). Research progress on mechanism of traditional Chinese medicine treating precancerous lesions of gastric cancer. Journal of Practical Traditional Chinese Internal Medicine, 37(2), 20-24.
[3] Gullo, I., Grillo, F., Mastracci, L., et al. (2020). Precancerous lesions of the stomach, gastric cancer and hereditary gastric cancer syndromes. Pathologica, 112(3), 166-185. https://doi.org/10.32074/1591-951X-166
[4] Dou, P., Song, R., Yao, L., et al. (2024). Research status of traditional Chinese medicine intervention in precancerous lesions of gastric cancer. The Chinese Journal of Clinical Pharmacology, 40(22), 3343-3347.
[5] Wen, Y., Jiang, A., Ma, W., et al. (2019). Advances on Chinese medicine in the treatment of precancerous lesions of gastric cancer. Guiding Journal of Traditional Chinese Medicine and Pharmacy, 25(13), 57-60.
[6] Wang, P., Li, P., Chen, H. L., et al. (2022). Guidelines for clinical management of integrated gastric precancerous lesions in China. Chinese Journal of Integrated Traditional and Western Medicine on Digestion, 30(3), 163-183.
[7] Liu, M., Yin, D., Zhang, Y., et al. (2024). Effect of Xiao Chaihu Decoction and Xiangsha Liujunzi Decoction on the changes of gastric mucosal pathological scores and gastrointestinal hormones in patients with chronic atrophic gastritis of liver stagnation and spleen deficiency type. Journal of Guangzhou University of Traditional Chinese Medicine, 41(9), 2326-2332.
[8] Zhou, J. (2023). Preliminary study on curative effect of Shengyang Yiwei Decoction on chronic atrophic gastritis with spleen and stomach weakness. World Journal of Complex Medicine, 9(6), 135-137, 141.
[9] Lv, A., Du, Q., & Jing, Z. (2024). Analysis of the therapeutic effect of Banxia Xiexin Decoction combined with quadruple therapy in the treatment of precancerous lesions in chronic atrophic gastritis. Clinical Journal of Traditional Chinese Medicine, 36(6), 1139-1143.
[10] Hong, W., Lu, B., & Li, Z., et al. (2020). Clinical efficacy of Huangqi Jianzhong Decoction in the treatment of gastric precancerous lesions. Chinese Journal of Gerontology, 40(12), 2503-2505.
[11] Xu, X., & Wei, M. (2021). Comparative study of modified Huatan Xiaoyu Recipe and western medicine in the treatment of precancerous lesions of gastric cancer. Journal of Clinical Medicine in Practice, 25(17), 92-96.
[12] Zheng, B. (2024). Clinical efficacy and mechanism of action of Sancao Tiaowei Decoction in the treatment of precancerous lesions of gastric cancer with spleen deficiency and stasis of phlegm and blood syndrome based on network pharmacology study. [Doctoral dissertation, Zhejiang University of Chinese Medicine].
[13] Dai, M., & Zhang, S. (2023). Therapeutic effect of using Huayu Jiedu Tongluo Recipe in the treatment of stomach-collateral stasis-toxin type gastric precancerous lesion and its influence on the expression of inflammatory factors, COX-2, PG I and G-17. Journal of Sichuan of Traditional Chinese Medicine, 41(1), 118-122.
[14] Li, J., Liu, X., & Meng, C. (2024). Exploring the efficacy of Strengthening the Spleen and Resolving Blood Stasis Formula in the treatment of gastric precancerous lesions based on the Correa cascade and its effect on the expression of inflammatory factors in patients. Modern Interventional Diagnosis and Treatment in Gastroenterology, 29(1), 68-73.
[15] Ye, G., Li, K., Jiang, W., et al. (2023). Clinical observation on the effects of Weiqi Decoction in the treatment of chronic atrophic gastritis with spleen and stomach deficiency. Chinese Journal of Integrated Traditional and Western Medicine on Digestion, 31(8), 595-599.
[16] Zhang, H., Zhou, X., & Cao, G., et al. (2024). Intervention effect of Weifuchun on precancerous lesions of gastric cancer rats based on PI3K/Akt signaling pathway. World Journal of Integrated Traditional and Western Medicine, 19(4), 689-693.
[17] Zhu, X., Li, S., Liu, J., et al. (2022). Efficacy of Moluodan in patients with gastric intestinal metaplasia: Analysis of 104 cases. Chinese Journal of Gastroenterology, 27(12), 717-722.
[18] Dai, J., Jin, H., & Meng, L., et al. (2017). Multi-center randomized clinical study of the effect of Curcuma and Pseudo-ginseng on chronic atrophic gastritis. Modern Chinese Clinical Medicine, 24(6), 15-19.
[19] Ye, C., He, Y., & Tang, S., et al. (2024). Clinical study on the effects of Yiweining Capsules combined with Rebamipide Tablet in treating chronic atrophic gastritis with spleen-stomach Qi deficiency syndrome. Chinese Journal of Information on Traditional Chinese Medicine, 31(1), 142-146.
[20] Jin, J., Zhong, H., & Liu, Q., et al. (2022). Comparison of stimulation-induced local changes of expression of local Meckel cell-related proteins and neuropeptides and number of mast cells among acupuncture and moxibustion alone or in combination in chronic atrophic gastritis rats. Acupuncture Research, 47(3), 203-208.
[21] Wang, F., Ye, H., & Chen, X., et al. (2021). Therapeutic efficacy and effect on serum MTL, SS, and GAS levels of chronic atrophic gastritis of spleen and stomach deficiency and cold type by combining Yuanluo Tongjing Acupuncture with Hao Huo Pins. Journal of Sichuan of Traditional Chinese Medicine, 39(8), 195-198.
[22] Guo, Y., & Zhou, F. (2018). Therapeutic efficacy of self-proposed stomach nourishing soup combined with acupoint burrowing in the treatment of chronic atrophic gastritis. Modern Journal of Integrated Traditional Chinese and Western Medicine, 27(26), 2893-2896.
[23] Sun, X., Lv, G., & Jia, J., et al. (2020). Clinical observation on Hewei Zhitong granule combined with auricular acupoint pressing bean in treating Hp positive chronic atrophic gastritis. Chinese Journal of Integrated Traditional and Western Medicine on Digestion, 28(7), 494-498.
[24] Ma, G., Li, L., & Song, Y., et al. (2024). Clinical study on Huangqi Jianzhong Decoction combined with acupoint application in the treatment of atrophic gastritis of spleen and stomach deficiency cold type. Chinese Health Care, 42(22), 18-21.
Published
2024-12-30
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